Scientists have discovered the main causes of migraines

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Scientists have discovered the main causes of migraines

Australian scientists, while studying the effect of metabolism on the development of cardiovascular diseases, discovered a previously unknown relationship of three metabolites with the development of migraine.

The research results are published in The American Journal of Human Genetics. According to the source, scientists have found three metabolites – metabolic products – when the level of which changes in a person, migraine occurs. In the course of research, specialists studied 316 unique metabolites in their connection with the development of migraine. Among them, for the most part, lipids and organic acids, the potential for the development of migraine was found, and in three there was a direct cause-and-effect relationship.

One of these substances was docosahexaenoic acid, which belongs to the class of Omega-3 fatty acids, with a reduced level of which there is a risk of developing migraines. In contrast, high levels of lysophosphatidylethanolamine 20: 4, a substance that blocks the production of the anti-inflammatory molecule anandamide, has also been found to cause migraines. This number includes the previously unexplored metabolite X-11315, the presence of which also affects the risk of developing migraine.

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