Securing success: why it is important to get a second shot

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Securing success: why it is important to get a second shot

Epidemiologist explains the importance of the second COVID-19 vaccination

Humoral immunity to COVID-19 lasts a maximum of three months after the first vaccination against coronavirus. To develop more reliable and long-lasting T-cell immunity, a second dose of the drug is needed, reports RIA Novosti with reference to the deputy head for scientific work of the Central Research Institute of Epidemiology of Rospotrebnadzor Alexander Gorelov.

“Humoral immunity [after the first vaccination] is unstable and short-lived, it lasts for 2-3 months. Therefore, to consolidate the success, a second dose of the vaccine is needed, ”said a corresponding member of the Russian Academy of Sciences.

Gorelov added that the effectiveness of the first dose is “reduced to naught” if a person misses the second injection after 21 days. He noted that in ideal conditions, 45 days should pass between the two vaccinations, but this period has been shortened due to the pandemic.

On April 14, Russian President Vladimir Putin said that after the second injection from the coronavirus, he did not feel any side effects. According to the head of state, after the first dose he had “good immunity.”

“I also got the second vaccination. I hope that everything will be fine. Not even that I hope, I am sure of this, ”Putin said. Presidential press secretary Dmitry Peskov told reporters shortly thereafter that Putin was “in good health, in a normal working condition.”

It is important to understand that being vaccinated against COVID-19 does not mean that the person vaccinated cannot infect others. This was stated by the Deputy Prime Minister of the Russian Federation Tatyana Golikova.

“For now, do not neglect PCR testing. So far we have not accumulated such a volume of information so that we can clearly say that if you are vaccinated, you are absolutely not dangerous to anyone, ”she said.

In January, acting Director of the N.I. Smorodintsev of the Ministry of Health of the Russian Federation Dmitry Lioznov also said that a vaccinated person can release the “picked up” pathogen into the external environment.

“A vaccinated person, he is protected, his disease does not develop, but the pathogen can get on the mucous membranes, remain there for some time and be released into the external environment,” the doctor emphasized.

As of the beginning of May, about 9 million citizens of the Russian Federation were vaccinated against coronavirus (both doses). Another 13 million were vaccinated with the first component of the vaccine. For the formation of population immunity, which would provide all-Russian protection against coronavirus, it is necessary to vaccinate about 70 million Russians. According to Golikova, from 200 to 300 thousand people are vaccinated against COVID-19 every day in the Russian Federation. Sometimes, the Deputy Prime Minister added, the number of those vaccinated can be even higher.

Now in Russia three drugs are used for vaccination: the world's first vaccine “Sputnik V”, the drug “CoviVac” and “EpiVacCorona”. Sputnik is the most popular in Russian medical institutions, but other drugs are also effective.

Earlier, the Scientific Center of Virology and Biotechnology “Vector” announced that it had begun trials of the three-time administration of “EpiVacCorona” in humans.

“The effect of the increase and duration of immunity has been confirmed, primarily in primates,” said Alexander Ryzhikov, head of the center's department of zoonotic infections and influenza.

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